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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: FOX{D1,D2}.p2

Z-value: 2.126

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_141294682	4.416	NM_018717	MAML3	mastermind-like 3 (Drosophila)
chr10_+_63478974	4.243		ARID5B	AT rich interactive domain 5B (MRF1-like)
chr17_+_56109940	3.779	NM_001099432 NM_017679	BCAS3	breast carcinoma amplified sequence 3
chr6_-_159386007	3.704	NM_054114 NM_138810 NM_152133	TAGAP	T-cell activation RhoGTPase activating protein
chr14_+_22136968	3.304	NM_022060	ABHD4	abhydrolase domain containing 4
chr6_+_12398514	3.212	NM_001168319 NM_001955	EDN1	endothelin 1
chr1_+_144149794	3.126	NM_006472	TXNIP	thioredoxin interacting protein
chr16_+_54070302	3.081	NM_004530	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr2_-_69033515	3.038	NM_182536	GKN2	gastrokine 2
chr3_-_170348215	2.898	NM_001164000	MECOM	MDS1 and EVI1 complex locus
chr6_+_149109841	2.757	NM_005715	UST	uronyl-2-sulfotransferase
chr2_-_192419896	2.742		SDPR	serum deprivation response
chr6_-_31658044	2.720	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr2_-_172458970	2.599	NM_003705	SLC25A12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr1_-_12599934	2.578	NM_004753	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr14_+_23937766	2.538	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr8_-_29263714	2.461	NM_001394	DUSP4	dual specificity phosphatase 4
chr11_-_10630408	2.445	NM_001098579	MRVI1	murine retrovirus integration site 1 homolog
chr5_-_42847716	2.425	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr20_+_62357490	2.412	NM_001104925 NM_018257	PCMTD2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr17_+_64922420	2.347	NM_002758	MAP2K6	mitogen-activated protein kinase kinase 6
chr13_+_109932934	2.339		COL4A2	collagen, type IV, alpha 2
chr6_+_139136349	2.336	NM_015439	CCDC28A	coiled-coil domain containing 28A
chr10_-_44794146	2.335	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr5_+_40877053	2.312	NM_032587	CARD6	caspase recruitment domain family, member 6
chr1_+_183970093	2.311	NM_031935	HMCN1	hemicentin 1
chr6_+_112481970	2.287	NM_003880 NM_198239	WISP3	WNT1 inducible signaling pathway protein 3
chr17_-_36559579	2.281	NM_033188	KRTAP4-5	keratin associated protein 4-5
chr16_+_11966464	2.204	NM_001192	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr2_-_71307705	1.976	NM_020459	PAIP2B	poly(A) binding protein interacting protein 2B
chr12_-_28014151	1.963	NM_198964 NM_198966	PTHLH	parathyroid hormone-like hormone
chr2_+_65136989	1.945	NM_015147	CEP68	centrosomal protein 68kDa
chr2_-_151854619	1.916	NM_004688	NMI	N-myc (and STAT) interactor
chr6_-_134415311	1.908	NM_145176	SLC2A12	solute carrier family 2 (facilitated glucose transporter), member 12
chr2_-_101457596	1.864	NM_001145664	RFX8	regulatory factor X, 8
chr4_-_74704964	1.838	NM_177532 NM_201431	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr2_-_170138558	1.823	NM_024622	FASTKD1	FAST kinase domains 1
chr2_+_178893216	1.818	NM_145739	OSBPL6	oxysterol binding protein-like 6
chr4_-_111339201	1.809	NM_001130721 NM_024090	ELOVL6	ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr2_-_192420168	1.806	NM_004657	SDPR	serum deprivation response
chr5_+_90711887	1.786		LOC100129716	hypothetical LOC100129716
chr6_-_152664906	1.781		SYNE1	spectrin repeat containing, nuclear envelope 1
chr12_+_12935222	1.745	NM_003979	GPRC5A	G protein-coupled receptor, family C, group 5, member A
chr13_+_96672705	1.713		MBNL2	muscleblind-like 2 (Drosophila)
chr17_-_34262862	1.708		RPL23	ribosomal protein L23
chr7_+_129693938	1.670	NM_001869	CPA2	carboxypeptidase A2 (pancreatic)
chr2_+_12774264	1.639	NM_021643	TRIB2	tribbles homolog 2 (Drosophila)
chr5_-_159778621	1.569	NM_006425	SLU7	SLU7 splicing factor homolog (S. cerevisiae)
chr2_-_68400516	1.555	NM_001111101 NM_015463	CNRIP1	cannabinoid receptor interacting protein 1
chr12_+_97513644	1.522		SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr6_+_32230172	1.516		PPT2	palmitoyl-protein thioesterase 2
chr20_+_47862782	1.510		SLC9A8	solute carrier family 9 (sodium/hydrogen exchanger), member 8
chr20_+_56397568	1.490	NM_001195677 NM_004738	VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C
chr10_-_45410197	1.484	NM_001002265 NM_145021	MARCH8	membrane-associated ring finger (C3HC4) 8
chr5_-_142046175	1.481	NM_033136	FGF1	fibroblast growth factor 1 (acidic)
chr20_+_254205	1.476	NM_006943	SOX12	SRY (sex determining region Y)-box 12
chr2_-_134042500	1.468	NM_207363 NM_207481	NCKAP5	NCK-associated protein 5
chr2_-_73860609	1.466	NM_003584	DUSP11	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr7_-_95063738	1.451	NM_002612	PDK4	pyruvate dehydrogenase kinase, isozyme 4
chr18_+_27152049	1.439	NM_001942	DSG1	desmoglein 1
chr12_+_46453196	1.434	NM_017842	SLC48A1	solute carrier family 48 (heme transporter), member 1
chr1_+_13784553	1.431	NM_001006624 NM_001006625	PDPN	podoplanin
chr2_-_165133239	1.429		GRB14	growth factor receptor-bound protein 14
chr20_+_62266217	1.424		MYT1	myelin transcription factor 1
chr14_+_85069217	1.415
chr7_+_106596641	1.414	NM_012257	HBP1	HMG-box transcription factor 1
chr7_+_116238309	1.409		CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2
chr20_+_62266270	1.399	NM_004535	MYT1	myelin transcription factor 1
chr16_-_56389176	1.396	NM_001130099	KIFC3	kinesin family member C3
chr12_-_51629874	1.393		KRT8	keratin 8
chr22_-_16127520	1.353		CECR3	cat eye syndrome chromosome region, candidate 3
chr8_+_100025806	1.342	NM_001142462 NM_053001	OSR2	odd-skipped related 2 (Drosophila)
chr11_+_10433241	1.326	NM_001025389	AMPD3	adenosine monophosphate deaminase 3
chr2_+_149119029	1.318	NM_015630	EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr1_-_20682541	1.281
chr11_-_71429747	1.276		NUMA1	nuclear mitotic apparatus protein 1
chr14_-_105817101	1.273
chr3_-_71196696	1.268		FOXP1	forkhead box P1
chr11_+_101488380	1.268	NM_001195045	YAP1	Yes-associated protein 1
chr14_-_22358752	1.268	NM_001126106	SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr20_+_43943254	1.267	NM_080603	ZSWIM1	zinc finger, SWIM-type containing 1
chr4_+_124537334	1.264	NM_199327	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr3_+_115099007	1.263	NM_001172105	GRAMD1C	GRAM domain containing 1C
chr17_+_9686572	1.257		GLP2R	glucagon-like peptide 2 receptor
chr14_-_30996348	1.247	NM_080664	C14orf126 HEATR5A	chromosome 14 open reading frame 126 HEAT repeat containing 5A
chr15_+_52092392	1.243	NM_001080534	UNC13C	unc-13 homolog C (C. elegans)
chr2_-_68952006	1.242	NM_014482	BMP10	bone morphogenetic protein 10
chr20_+_47862656	1.236	NM_015266	SLC9A8	solute carrier family 9 (sodium/hydrogen exchanger), member 8
chr6_+_32229771	1.235		PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr2_-_156897286	1.228	NM_006186	NR4A2	nuclear receptor subfamily 4, group A, member 2
chr11_-_101828563	1.225	NM_052932	TMEM123	transmembrane protein 123
chr11_-_46572073	1.216		AMBRA1	autophagy/beclin-1 regulator 1
chr17_-_61655915	1.210	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr11_-_85074848	1.203	NM_152723	CCDC89	coiled-coil domain containing 89
chr10_+_63331018	1.181	NM_032199	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr2_-_128358903	1.173	NM_031445	AMMECR1L	AMME chromosomal region gene 1-like
chr17_-_53847937	1.173		RNF43	ring finger protein 43
chr8_+_40130143	1.162	NM_020130	C8orf4	chromosome 8 open reading frame 4
chr14_-_21108714	1.157	NM_001005465	OR10G3	olfactory receptor, family 10, subfamily G, member 3
chr3_-_187309442	1.155	NM_004454	ETV5	ets variant 5
chr2_-_165259334	1.144		COBLL1	COBL-like 1
chr14_+_22911857	1.143	NM_172314 NM_022789	IL25	interleukin 25
chr2_+_196229715	1.141	NM_001127257	SLC39A10	solute carrier family 39 (zinc transporter), member 10
chr7_+_154351087	1.123		LOC100132707	hypothetical LOC100132707
chr2_-_213724577	1.120	NM_001079526	IKZF2	IKAROS family zinc finger 2 (Helios)
chr9_-_72218098	1.116		KLF9	Kruppel-like factor 9
chr6_+_134800533	1.116		LOC154092	hypothetical LOC154092
chr17_-_36719030	1.115	NM_001146182	KRTAP16-1	keratin associated protein 16-1
chr2_+_172658453	1.099	NM_001038493 NM_178120	DLX1	distal-less homeobox 1
chr2_+_101680594	1.097	NM_004834 NM_145686 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_96351345	1.095
chr5_+_137701601	1.091	NM_016605	FAM53C	family with sequence similarity 53, member C
chr20_+_2030527	1.087	NM_080836	STK35	serine/threonine kinase 35
chr2_+_102602579	1.081	NM_003048	SLC9A2	solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr4_-_140443061	1.075	NM_001184987 NM_001184988 NM_001184989 NM_001184990	NDUFC1	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr1_-_28376041	1.066	NM_000952	PTAFR	platelet-activating factor receptor
chr16_+_85169615	1.064	NM_005250	FOXL1	forkhead box L1
chr12_-_46499834	1.061	NM_001098416 NM_015401	HDAC7	histone deacetylase 7
chr8_-_134378630	1.053	NM_001135242 NM_006096	NDRG1	N-myc downstream regulated 1
chr1_+_150753601	1.052	NM_019060	CRCT1	cysteine-rich C-terminal 1
chr1_-_85816520	1.047	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr3_+_137224266	1.044	NM_181897	PPP2R3A	protein phosphatase 2, regulatory subunit B'', alpha
chr17_-_36507900	1.043	NM_031960	KRTAP4-8	keratin associated protein 4-8
chr1_-_166373434	1.041		GPR161	G protein-coupled receptor 161
chr18_+_54681040	1.038	NM_018181	ZNF532	zinc finger protein 532
chr7_+_91408086	1.037	NM_005751 NM_147185	AKAP9	A kinase (PRKA) anchor protein (yotiao) 9
chr5_-_158567411	1.018	NM_144726	RNF145	ring finger protein 145
chr1_-_151780720	1.003	NM_002962	S100A5	S100 calcium binding protein A5
chr7_-_140270749	1.001	NM_004333	BRAF	v-raf murine sarcoma viral oncogene homolog B1
chr6_+_32229599	0.994	NM_005155	PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr4_+_109763119	0.976		RPL34	ribosomal protein L34
chr7_-_99536214	0.971	NM_182776	MCM7	minichromosome maintenance complex component 7
chr17_-_36528113	0.966	NM_033059	KRTAP4-11	keratin associated protein 4-11
chr3_-_71715431	0.964	NM_001012505 NM_032682	FOXP1	forkhead box P1
chr2_-_208598452	0.963	NM_001080475	PLEKHM3	pleckstrin homology domain containing, family M, member 3
chr14_-_34078532	0.962	NM_018453	EAPP	E2F-associated phosphoprotein
chr9_-_93163965	0.959		AUH	AU RNA binding protein/enoyl-CoA hydratase
chr10_+_111959978	0.959	NM_001008541	MXI1	MAX interactor 1
chr4_+_86615275	0.958	NM_001025616	ARHGAP24	Rho GTPase activating protein 24
chr5_-_142045770	0.949	NM_000800	FGF1	fibroblast growth factor 1 (acidic)
chr8_+_70567581	0.947	NM_001128205 NM_001128206	SULF1	sulfatase 1
chr6_-_87861492	0.947	NM_000735	CGA	glycoprotein hormones, alpha polypeptide
chr6_-_168222645	0.944	NM_024919	FRMD1	FERM domain containing 1
chr20_+_31287462	0.941	NM_016583 NM_130852	PLUNC	palate, lung and nasal epithelium associated
chr1_+_40635058	0.939	NM_001198980	SMAP2	small ArfGAP2
chr1_+_204305506	0.936	NM_001123168	FAM72B FAM72A	family with sequence similarity 72, member B family with sequence similarity 72, member A
chr11_-_46572160	0.935		AMBRA1	autophagy/beclin-1 regulator 1
chr6_+_106653429	0.934	NM_182907	PRDM1	PR domain containing 1, with ZNF domain
chr2_-_37047113	0.933	NM_003162	STRN	striatin, calmodulin binding protein
chr6_+_31081707	0.933	NM_001198815	PBMUCL1	panbronchiolitis related mucin-like 1
chr2_-_175741096	0.931	NM_001880	ATF2	activating transcription factor 2
chr3_+_38322430	0.930	NM_004803	SLC22A14	solute carrier family 22, member 14
chr16_-_46957284	0.922	NM_001006610	SIAH1	seven in absentia homolog 1 (Drosophila)
chr2_-_26058941	0.922	NM_002254	KIF3C	kinesin family member 3C
chr16_-_82707882	0.919		MBTPS1	membrane-bound transcription factor peptidase, site 1
chr15_-_61236532	0.919	NM_015920	RPS27L	ribosomal protein S27-like
chr2_-_188127294	0.914		TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr19_+_17440577	0.910		SLC27A1	solute carrier family 27 (fatty acid transporter), member 1
chr5_+_137701852	0.910		FAM53C	family with sequence similarity 53, member C
chr11_-_102331643	0.903	NM_002427	MMP13	matrix metallopeptidase 13 (collagenase 3)
chr16_-_46957254	0.903		SIAH1	seven in absentia homolog 1 (Drosophila)
chr5_+_137701855	0.901		FAM53C	family with sequence similarity 53, member C
chr4_+_140806536	0.899		MGST2	microsomal glutathione S-transferase 2
chr1_+_87567136	0.898		LMO4	LIM domain only 4
chr14_+_23654307	0.897	NM_181357	DCAF11	DDB1 and CUL4 associated factor 11
chr15_+_78520634	0.896		ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr1_-_28375722	0.894	NM_001164723	PTAFR	platelet-activating factor receptor
chr2_-_213723298	0.892	NM_016260	IKZF2	IKAROS family zinc finger 2 (Helios)
chr6_-_30151526	0.884	NM_170769 NM_025236	RNF39	ring finger protein 39
chr9_-_93164015	0.876	NM_001698	AUH	AU RNA binding protein/enoyl-CoA hydratase
chr9_+_117955890	0.873	NM_002581	PAPPA	pregnancy-associated plasma protein A, pappalysin 1
chr12_-_28016182	0.872	NM_002820 NM_198965	PTHLH	parathyroid hormone-like hormone
chr8_+_70567634	0.867		SULF1	sulfatase 1
chr15_-_29070909	0.861	NM_017762	MTMR10	myotubularin related protein 10
chr2_+_188865796	0.855		GULP1	GULP, engulfment adaptor PTB domain containing 1
chr12_+_123339662	0.852	NM_181709	FAM101A	family with sequence similarity 101, member A
chr20_-_1396336	0.850	NM_016143 NM_018839 NM_182483	NSFL1C	NSFL1 (p97) cofactor (p47)
chr16_-_74024750	0.846	NM_006324	CFDP1	craniofacial development protein 1
chr2_-_197883569	0.844		ANKRD44	ankyrin repeat domain 44
chr12_+_105220638	0.842	NM_152772	TCP11L2	t-complex 11 (mouse)-like 2
chr6_+_135544214	0.840		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr20_-_7869068	0.840	NM_017545	HAO1	hydroxyacid oxidase (glycolate oxidase) 1
chr6_-_105734535	0.839	NM_022361	POPDC3	popeye domain containing 3
chr17_+_34115383	0.839	NM_005937	MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr6_+_123152044	0.839		SMPDL3A	sphingomyelin phosphodiesterase, acid-like 3A
chr2_-_160181206	0.838	NM_013450	BAZ2B	bromodomain adjacent to zinc finger domain, 2B
chr17_-_31616071	0.837	NM_001001418 NM_032258	TBC1D3B TBC1D3C TBC1D3G TBC1D3F	TBC1 domain family, member 3B TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3F
chr17_-_60088459	0.837		SMURF2	SMAD specific E3 ubiquitin protein ligase 2
chr1_+_51208499	0.835		CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr2_+_196230096	0.832	NM_020342	SLC39A10	solute carrier family 39 (zinc transporter), member 10
chr9_-_97319067	0.818	NM_001083602 NM_001083603	PTCH1	patched 1
chr11_+_1607580	0.817	NM_001001480	KRTAP5-5	keratin associated protein 5-5
chr10_+_18729518	0.816	NM_201570	CACNB2	calcium channel, voltage-dependent, beta 2 subunit
chr19_-_52426055	0.815	NM_014417	BBC3	BCL2 binding component 3
chr12_+_98565663	0.814	NM_153364	FAM71C	family with sequence similarity 71, member C
chr17_-_31882135	0.804	NM_001001418 NM_001040282	TBC1D3C TBC1D3G TBC1D3	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3
chr6_+_12120709	0.803	NM_002114	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1
chr2_+_151974849	0.799	NM_001177665	RIF1	RAP1 interacting factor homolog (yeast)
chr2_-_87156616	0.797		LOC285074	anaphase promoting complex subunit 1 pseudogene
chr9_+_132558972	0.797	NM_014285	EXOSC2	exosome component 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.63	7.65e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.61	1.93e-02	GO:0032774	RNA biosynthetic process
1.41	3.62e-02	GO:0010467	gene expression
1.62	3.95e-02	GO:0006351	transcription, DNA-dependent

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
3.44	2.24e-03	GO:0045095	keratin filament
1.09	1.40e-02	GO:0005622	intracellular
1.19	1.54e-02	GO:0005634	nucleus
1.09	3.49e-02	GO:0044424	intracellular part
1.11	4.93e-02	GO:0043226	organelle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.61	2.12e-03	GO:0001071	nucleic acid binding transcription factor activity
1.61	2.12e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
1.90	2.35e-02	GO:0003712	transcription cofactor activity
1.90	2.51e-02	GO:0000988	protein binding transcription factor activity
1.90	2.51e-02	GO:0000989	transcription factor binding transcription factor activity

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